When the weeknight dinner question looms large, chicken spaghetti is like a trusty superhero swooping in to save the day. It’s comforting, easy to whip up, and endlessly versatile. The beauty of this dish lies in its ability to adapt to every taste bud, pantry shelf, and mood.
Whether you love creamy indulgence or a punch of spice, we’ve got you covered. Here, I’ll walk you through 10 creative variations of chicken spaghetti that you can make your own. Grab your fork, and let’s dig in!
1. Creamy Classic Chicken Spaghetti
Sometimes, you can’t go wrong with the basics. Creamy chicken spaghetti is the comfort food you never knew you needed. Imagine tender shredded chicken swirled into pasta enveloped in a rich, velvety cream sauce.
The magic starts with a simple white sauce made from butter, flour, and milk, but the real hero of this dish is a generous pinch of garlic powder and paprika. Some folks blend in cream cheese or a handful of shredded cheddar for that extra lusciousness. This recipe is fully customizable—add sautéed mushrooms, diced bell peppers, or steamed broccoli if you like a veggie boost.
Find the full recipe waiting for you to try at home!
2. Spicy Cajun Chicken Spaghetti
Turn up the heat with a spicy Cajun twist on chicken spaghetti. Start with blackened chicken breast seasoned with Cajun spices like paprika, cayenne, garlic powder, and thyme. Cook your chicken until it’s perfectly juicy and flavorful, then thinly slice it to add to your pasta. The sauce is where the real fire happens.
Combine heavy cream with more Cajun seasoning, diced tomatoes, and Parmesan cheese. You’ll end up with a creamy yet fiery sauce that hugs every strand of pasta. This dish shines with extras. Toss in slices of andouille sausage or diced bell peppers for a true Southern-inspired feast. And if you want to dial it up another notch, sprinkle crushed red pepper flakes over the top before serving.
Get inspired to make it your own by checking out the full recipe details!
3. Mexican Chicken Spaghetti
Say hello to taco night in pasta form. Mexican-style chicken spaghetti combines the bold flavors of Tex-Mex with the comfort of pasta. Start with shredded chicken, seasoned with taco spices like cumin, chili powder, and garlic. The sauce for this recipe is a creamy yet spicy blend of sour cream, diced green chiles, cheddar cheese, and a splash of salsa for that tangy kick.
Layer everything together, pop it in the oven, and bake until bubbly. Add a crunchy topping of tortilla strips or crushed chips for extra texture and fun. Serve with a side of guacamole or a dollop of sour cream to take things to the next level.
Discover the step-by-step guide to creating this fiesta in a bowl!
4. Pesto Chicken Spaghetti
For a fresh and herbaceous twist, pesto chicken spaghetti is the way to go. The star of this dish is a vibrant green pesto sauce made from basil, Parmesan, olive oil, and garlic. Pair this zesty sauce with grilled or roasted chicken breast. Shred or chop the chicken and toss it with freshly cooked spaghetti and spoonfuls of the pesto sauce.
This dish is all about simplicity, letting the flavors shine through without overcomplicating things. Want to get fancy? Add some sun-dried tomatoes or toasted pine nuts for a pop of flavor and crunch. It’s the kind of recipe that feels elegant enough for a dinner party but is so easy it works on a busy Monday, too.
You’ll love how light and flavorful this recipe is. Check out the full how-to now!
5. Chicken Spaghetti Casserole
Few things say cozy like a baked casserole, and this cheesy chicken spaghetti casserole is the ultimate family favorite. Start with a hearty helping of shredded chicken and al dente spaghetti. The sauce is a mix of cream of chicken soup, cream of mushroom soup, and plenty of shredded cheese.
Stir everything together, toss it into a baking dish, and top with a layer of sharp cheddar or Colby Jack. Then bake until golden and gooey. For a bit of crunch, sprinkle crushed crackers or breadcrumbs on top before baking. Add some green onions or a side salad for a little color, and watch the smiles light up around the table.
The recipe is just waiting for you to try it step by step!
6. Lemon Garlic Chicken Pasta Spaghetti
Brighten up your weeknight dinner with this light and zesty lemon garlic variation. It all starts with juicy grilled chicken, seasoned with salt, pepper, and a touch of oregano. The sauce is a simple yet tangy mix of garlic, olive oil, fresh lemon juice, and grated Parmesan.
It’s a no-cream, no-fuss recipe that’s perfect for those who prefer a lighter pasta dish. Add a sprinkle of fresh parsley or even capers for a briny pop. Pair it with a side of garlic bread, and you’ve got yourself a dish that feels indulgent but is shockingly easy to make.
Find out exactly how to whip this up with a simple guide!
7. Buffalo Chicken Spaghetti
If you’re a Buffalo sauce lover, this recipe is for you. Buffalo chicken spaghetti is creamy, spicy, and impossible to resist. Start with shredded chicken and mix it with a rich, cheesy sauce made from cream cheese, ranch dressing, and a generous splash of your favorite buffalo sauce.
Toss everything together with spaghetti and top with a sprinkle of blue cheese or shredded mozzarella. For that crunchy finish, bake the mixture briefly or even add a handful of crushed pretzels on top for texture. Serve with celery sticks or a garden salad to balance out the bold flavors.
Get excited to try this fiery favorite by checking out the full recipe!
8. Garlic Parmesan Chicken Spaghetti
Bring out the flavor of garlic and cheese in this rich and satisfying dish. Garlic Parmesan chicken spaghetti starts with a creamy garlic Alfredo-style sauce. Cook minced garlic in butter until fragrant, then whisk in heavy cream, Parmesan cheese, and a touch of nutmeg.
Toss in shredded rotisserie chicken and cooked pasta, mixing everything until it’s silky smooth. You can elevate this dinner classic with crispy bacon bits, peas, or fresh spinach for added texture and color. It’s one of those recipes you’ll want to add to your regular rotation.
Try making this tonight by following the simple recipe instructions!
9. Sesame Chicken Spaghetti
For something a little unexpected, why not try an Asian-inspired version of chicken spaghetti? Swap traditional marinara or Alfredo for a savory sesame sauce. Use soy sauce, sesame oil, honey, and ginger as the base, then toss in your spaghetti with shredded chicken and sautéed veggies like bell peppers and snap peas.
Top with a sprinkle of sesame seeds, chopped green onions, or even a drizzle of sriracha for some heat. This dish brings an exciting twist to spaghetti night while staying familiar enough for everyone to enjoy.
Check out how to make this delightful twist today!
10. Sicilian Chicken Spaghetti
Last but not least, this Sicilian recipe combines chicken, pasta, and the bold, fresh flavors of the Sicilian in one bowl. Sauté shredded chicken with olive oil, garlic, and plenty of oregano. Then, toss with spaghetti, diced tomatoes, black olives, and crumbled feta cheese.
Finish with a drizzle of extra virgin olive oil and a sprinkle of fresh parsley for brightness. This dish pairs beautifully with a crisp cucumber salad or garlic pita bread. It’s wholesome, filling, and packed with zingy flavors.
Learn the step-by-step method to bring this to your dinner table tonight!
11. Chicken Alfredo Spaghetti
Rich, creamy, and oh-so-indulgent, chicken Alfredo spaghetti is a perfect dish for pasta lovers. This recipe starts with grilled or shredded chicken tossed in a luscious homemade Alfredo sauce. You’ll need butter, heavy cream, garlic, and Parmesan cheese to create that velvety texture you love.
What makes this variation extra special is the opportunity to customize it. Add steamed broccoli for a burst of color and nutrition, or throw in sun-dried tomatoes for a hint of sweetness. Sprinkle some parsley on top for a fresh, herby finish, and don’t forget the garlic bread on the side.
It’s easier to make than it sounds! Go check out the full recipe today and treat yourself.
12. Chicken Spaghetti Carbonara
Love carbonara? You’ll love this twist with chicken added to the mix. Start with al dente spaghetti tossed in a creamy yet light sauce made from eggs, Parmesan cheese, and cooked bacon. Stir in diced or shredded chicken to make it heartier.
The key to this dish is timing. To get that silky sauce, mix the egg and cheese mixture with the hot spaghetti quickly, ensuring the eggs don’t scramble. Top it with black pepper and extra Parmesan for bold flavors, and you’ve got a dinner that feels like a restaurant-style treat.
Check out how to make this decadent dish with easy instructions!
13. Chicken and Spinach Spaghetti
Get your greens and comfort food all in one dish with this healthy twist on chicken spaghetti. This recipe combines shredded chicken, sautéed spinach, and a creamy white sauce. Stir them together with cooked spaghetti and layer everything into a baking dish.
Top with a generous sprinkle of mozzarella and Parmesan, then bake until golden and bubbly. It’s a great way to sneak in vegetables while still creating a dish the whole family will enjoy. This one works beautifully as a make-ahead meal for busy days.
You’re going to love this one—find the full recipe now!
14. BBQ Chicken Spaghetti
Take a bold and smoky approach with BBQ chicken spaghetti. Start by tossing shredded chicken with your favorite barbecue sauce. Combine it with cooked spaghetti and a tangy tomato-based sauce.
For texture, add crispy fried onions or chopped scallions on top. The sweet and smoky flavors pair perfectly with coleslaw or baked beans on the side, making it a unique dinner option.
Check out the recipe and enjoy this creative twist!
15. Chicken Marsala Spaghetti
Turn the flavors of chicken Marsala into a pasta delight. This dish starts with chicken cooked in a rich Marsala wine sauce along with mushrooms, garlic, and butter. Toss the mixture with cooked spaghetti, and allow it to absorb all that savory goodness.
For added depth, sprinkle grated Parmesan cheese on top and garnish with chopped parsley. The result is a luxurious pasta dish that’s elegant enough for special occasions but simple enough to make for dinner any night.
It’s so tasty you’ll want to try it right away, so check out the recipe here!
16. Chicken Enchilada Spaghetti
Craving enchiladas but want spaghetti? Why not combine the two? Chicken enchilada spaghetti uses the bold flavors of red enchilada sauce, shredded chicken, and melted cheddar cheese. Toss everything with cooked spaghetti, then bake the dish until hot and bubbly.
Top with sliced black olives, chopped cilantro, or jalapeños for an added kick. Serve it with a squeeze of lime for a bright and zesty finish that screams fiesta on a plate.
Get all the details for this flavorful dish by following the full recipe here!
17. Greek-Inspired Chicken Spaghetti
Take your tastebuds to the Mediterranean with this Greek-inspired recipe. Toss shredded chicken and spaghetti with a dressing made from olive oil, lemon juice, garlic, and oregano. Add diced cucumbers, tomatoes, and olives for a refreshing crunch. Crumbled feta cheese ties it all together beautifully.
Serve it cold for a pasta salad vibe, or warm it slightly for a comforting dinner option. Pair with pita bread and hummus for a complete Mediterranean feast.
